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Recombinant Human Nanos homolog 1 (NANOS1)

ACP14174

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14174 Target NameNANOS1
Target SynonymsEC Rep1a; EC_Rep1a; NANO1_HUMAN; NANOS 1; Nanos homolog 1 (Drosophila); Nanos homolog 1; Nanos Homologue 1 (NANOS1); NANOS1; Nos 1; NOS-1; Nos1; OTTHUMP00000046853; Rep 1a; Rep1aFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-292
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8WY41
Background Information
  • Uniprot Id

    Q8WY41

  • Target Species

    Human

  • Target Name

    NANOS1

  • Target Full Name

    Nanos homolog 1

  • Target Function

    May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion.

  • Target Involvement

    Spermatogenic failure 12 (SPGF12)

  • Target Subcellular Location

    Cytoplasm, perinuclear region. Cytoplasm.

  • Target Protein Families

    Nanos family

  • Target Tissue Specificity

    Testis and ovary (at protein level). Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed during meiosis in spermat

  • Target Synonyms

    EC Rep1a; EC_Rep1a; NANO1_HUMAN; NANOS 1; Nanos homolog 1 (Drosophila); Nanos homolog 1; Nanos Homologue 1 (NANOS1); NANOS1; Nos 1; NOS-1; Nos1; OTTHUMP00000046853; Rep 1a; Rep1a

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