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| Cat.No | ACP08966 | Target Name | NES |
|---|---|---|---|
| Target Synonyms | ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; nes; NEST_HUMAN; Nestin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1321-1569aa |
| Mol Weight | 27.8kD | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P48681 |
|---|
Uniprot Id
P48681
Target Species
Human
Target Name
NES
Target Full Name
Nestin
Target Function
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Target Protein Families
Intermediate filament family
Target Tissue Specificity
CNS stem cells.
Target Research Area
Neuroscience
Target Synonyms
ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; nes; NEST_HUMAN; Nestin
Target Background
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
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