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| Cat.No | ACP16539 | Target Name | UNC5D |
|---|---|---|---|
| Target Synonyms | UNC5D; KIAA1777; UNC5H4; UNQ6012/PRO34692; Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UXZ4 |
|---|
Uniprot Id
Q6UXZ4
Target Species
Human
Target Name
UNC5D
Target Full Name
Netrin receptor UNC5D
Target Function
Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Unc-5 family
Target Synonyms
UNC5D; KIAA1777; UNC5H4; UNQ6012/PRO34692; Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D
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