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| Cat.No | ACP19064 | Target Name | NCDN |
|---|---|---|---|
| Target Synonyms | NCDN; KIAA0607; Neurochondrin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-729 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UBB6 |
|---|
Uniprot Id
Q9UBB6
Target Species
Human
Target Name
NCDN
Target Full Name
Neurochondrin
Target Function
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
Target Subcellular Location
Cytoplasm, cytosol. Endosome membrane; Lipid-anchor. Cell projection, dendrite. Cell junction, synapse, postsynapse.
Target Protein Families
Neurochondrin family
Target Tissue Specificity
Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. Weakly expressed in ovary, testis, fetal brain and small intestine.
Target Synonyms
NCDN; KIAA0607; Neurochondrin
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