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Recombinant Human Neurofibromin (NF1), Truncated

ACP23944

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23944 Target NameNF1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP21359
Background Information
  • Uniprot Id

    P21359

  • Target Species

    Human

  • Target Name

    NF1

  • Target Full Name

    Neurofibromin

  • Target Function

    Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.

  • Target Involvement

    Neurofibromatosis 1 (NF1); Leukemia, juvenile myelomonocytic (JMML); Watson syndrome (WTSN); Familial spinal neurofibromatosis (FSNF); Neurofibromatosis-Noonan syndrome (NFNS); Colorectal cancer (CRC)

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Tissue Specificity

    Detected in brain, peripheral nerve, lung, colon and muscle.

  • Target Research Area

    Cancer

  • Target Synonyms

    DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS

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