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| Cat.No | ACP09757 | Target Name | NEUROG3 |
|---|---|---|---|
| Target Synonyms | ATH4B; Atoh5; bHLHa7; Class A basic helix-loop-helix protein 7; Math4B; NEUROG3; Neurogenin-3; Neurogenin3; NGN-3; ngn3; NGN3_HUMAN; OTTHUMP00000019730; Protein atonal homolog 5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-214 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y4Z2 |
|---|
Uniprot Id
Q9Y4Z2
Target Species
Human
Target Name
NEUROG3
Target Full Name
Neurogenin-3
Target Function
Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
Target Involvement
Diarrhea 4, malabsorptive, congenital (DIAR4)
Target Subcellular Location
Nucleus.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
ATH4B; Atoh5; bHLHa7; Class A basic helix-loop-helix protein 7; Math4B; NEUROG3; Neurogenin-3; Neurogenin3; NGN-3; ngn3; NGN3_HUMAN; OTTHUMP00000019730; Protein atonal homolog 5
Target Background
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
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