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| Cat.No | ACP19460 | Target Name | NAV3 |
|---|---|---|---|
| Target Synonyms | NAV3; KIAA0938; POMFIL1; STEERIN3; Neuron navigator 3; Pore membrane and/or filament-interacting-like protein 1; Steerin-3; Unc-53 homolog 3; unc53H3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IVL0 |
|---|
Uniprot Id
Q8IVL0
Target Species
Human
Target Name
NAV3
Target Full Name
Neuron navigator 3
Target Function
May regulate IL2 production by T-cells. May be involved in neuron regeneration.
Target Involvement
A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome (PubMed:16166283). Translocation t(12;18)(q21;q21.2) (PubMed:16166283).
Target Subcellular Location
Nucleus outer membrane.
Target Protein Families
Nav/unc-53 family
Target Tissue Specificity
Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.
Target Synonyms
NAV3; KIAA0938; POMFIL1; STEERIN3; Neuron navigator 3; Pore membrane and/or filament-interacting-like protein 1; Steerin-3; Unc-53 homolog 3; unc53H3
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