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| Cat.No | ACP12429 | Target Name | NPAS1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-590 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q99742 |
|---|
Uniprot Id
Q99742
Target Species
Human
Target Name
NPAS1
Target Full Name
Neuronal PAS domain-containing protein 1
Target Function
May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH.
Target Subcellular Location
Nucleus.
Target Synonyms
NPAS1; BHLHE11; MOP5; PASD5; Neuronal PAS domain-containing protein 1; Neuronal PAS1; Basic-helix-loop-helix-PAS protein MOP5; Class E basic helix-loop-helix protein 11; bHLHe11; Member of PAS protein 5; PAS domain-containing protein 5
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