Home Products Uncategorized Recombinant Human NHP2-like protein 1 (NHP2L1)

Recombinant Human NHP2-like protein 1 (NHP2L1)

ACP09190

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Specifications

Cat.No	ACP09190	Target Name	SNU13
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-128	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P55769

Background Information

Uniprot Id

P55769
Target Species

Human
Target Name

SNU13
Target Full Name

NHP2-like protein 1
Target Function

Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Target Subcellular Location

Nucleus. Nucleus, nucleolus.
Target Protein Families

Eukaryotic ribosomal protein eL8 family
Target Tissue Specificity

Ubiquitous.
Target Research Area

Transcription
Target Synonyms

SNU13; NHP2L1; NHP2-like protein 1; High mobility group-like nuclear protein 2 homolog 1; OTK27; SNU13 homolog; hSNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1; N-terminally processed]
Target Background

Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.

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Recombinant Human NHP2-like protein 1 (NHP2L1)

Specifications

Immunogen Information

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