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Recombinant Human Nodal homolog (NODAL)

ACP13144

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Specifications

Cat.No	ACP13144	Target Name	NODAL
Target Synonyms	HTX5; MGC138230; Nodal; Nodal Growth Differentiation Factor; nodal homolog (mouse); Nodal homolog; Nodal; Mouse; Homolog; NODAL_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	238-347
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96S42

Background Information

Uniprot Id

Q96S42
Target Species

Human
Target Name

NODAL
Target Full Name

Nodal homolog
Target Function

Essential for mesoderm formation and axial patterning during embryonic development.
Target Involvement

Heterotaxy, visceral, 5, autosomal (HTX5)
Target Subcellular Location

Secreted.
Target Protein Families

TGF-beta family
Target Synonyms

HTX5; MGC138230; Nodal; Nodal Growth Differentiation Factor; nodal homolog (mouse); Nodal homolog; Nodal; Mouse; Homolog; NODAL_HUMAN
Target Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

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Recombinant Human Nodal homolog (NODAL)

Specifications

Immunogen Information

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