Recombinant Human Nuclear pore complex protein Nup107 (NUP107), Truncated

Uniprot Id

P57740

Target Species

Human

Target Name

NUP107

Target Full Name

Nuclear pore complex protein Nup107

Target Function

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis.

Target Involvement

Nephrotic syndrome 11 (NPHS11)

Target Subcellular Location

Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore.

Target Protein Families

Nucleoporin Nup84/Nup107 family

Target Tissue Specificity

Ubiquitously expressed in fetal and adult tissues.

Target Synonyms

107 kDa nucleoporin; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP107; NUP84; NUP84; yeast; homolog of; OTTHUMP00000240604; OTTHUMP00000240606

Target Background

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.