Recombinant Human Nuclear pore complex protein Nup85 (NUP85)

Cat.No	ACP11347	Target Name	NUP85
Target Synonyms	75-KD; Nucleoporin85; Nup 75; NUP 85; Nup75; nup85; NUP85_HUMAN; PCN; PCNT 1; PCNT; PCNT, formerly; PCNT1; Pericentrin; Pericentrin, formerly; Pericentrin-1; Pericentrin1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-656
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP11347

Target Name

NUP85

Target Synonyms

75-KD; Nucleoporin85; Nup 75; NUP 85; Nup75; nup85; NUP85_HUMAN; PCN; PCNT 1; PCNT; PCNT, formerly; PCNT1; Pericentrin; Pericentrin, formerly; Pericentrin-1; Pericentrin1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-656

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9BW27

Background Information

Uniprot Id

Q9BW27
Target Species

Human
Target Name

NUP85
Target Full Name

Nuclear pore complex protein Nup85
Target Function

Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade. Involved in nephrogenesis.
Target Subcellular Location

Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus membrane.
Target Protein Families

Nucleoporin Nup85 family
Target Research Area

Tags & Cell Markers
Target Synonyms

85 kDa nucleoporin; FLJ12549; FROUNT; Frount protein; Nuclear pore complex protein nucleoporin 85 kDa; nuclear pore complex protein nucleoporin Nup75; Nuclear pore complex protein Nup85; Nucleoporin 85; Nucleoporin 85kDa; Nucleoporin nucleoporin 85kDa; Nucleoporin Nup75; Nucleoporin NUP85; nucleoporin, 75-KD; Nucleoporin85; Nup 75; NUP 85; Nup75; nup85; NUP85_HUMAN; PCN; PCNT 1; PCNT; PCNT, formerly; PCNT1; Pericentrin; Pericentrin, formerly; Pericentrin-1; Pericentrin1
Target Background

This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants.

Recombinant Human Nuclear pore complex protein Nup85 (NUP85)

Specifications

Immunogen Information

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