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| Cat.No | ACP09786 | Target Name | EXOG |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 42-368 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y2C4 |
|---|
Uniprot Id
Q9Y2C4
Target Species
Human
Target Name
EXOG
Target Full Name
Nuclease EXOG, mitochondrial
Target Function
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
Target Subcellular Location
Mitochondrion inner membrane.
Target Protein Families
DNA/RNA non-specific endonuclease family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
Endo G like 1; Endo G-like 1; Endo/exonuclease (5'-3'); endonuclease G like; ENDOGL 1; ENDOGL1; ENDOGL2; Endonuclease G like 1; Endonuclease G like 2; Endonuclease G-like 1; ENGL a; ENGL; ENGL B; ENGLA; ENGLB; Exog; EXOG_HUMAN; MGC125944; MGC125945; mitochondrial; Nuclease EXOG; Nuclease EXOG mitochondrial
Target Background
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
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