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| Cat.No | ACP11524 | Target Name | NOL6 |
|---|---|---|---|
| Target Synonyms | NOL6; Nucleolar protein 6; Nucleolar RNA-associated protein; Nrap | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H6R4 |
|---|
Uniprot Id
Q9H6R4
Target Species
Human
Target Name
NOL6
Target Full Name
Nucleolar protein 6
Target Subcellular Location
Nucleus, nucleolus. Chromosome.
Target Protein Families
NRAP family
Target Synonyms
NOL6; Nucleolar protein 6; Nucleolar RNA-associated protein; Nrap
Target Background
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
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