Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP19649 | Target Name | NXN |
|---|---|---|---|
| Target Synonyms | FLJ12614; NRX; nucleoredoxin 1; Nucleoredoxin; Nxn; NXN_HUMAN; OTTHUMP00000115356; TRG 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-435 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6DKJ4 |
|---|
Uniprot Id
Q6DKJ4
Target Species
Human
Target Name
NXN
Target Full Name
Nucleoredoxin
Target Function
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
Nucleoredoxin family
Target Synonyms
FLJ12614; NRX; nucleoredoxin 1; Nucleoredoxin; Nxn; NXN_HUMAN; OTTHUMP00000115356; TRG 4
Target Background
This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
