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| Cat.No | ACP22078 | Target Name | ODAM |
|---|---|---|---|
| Target Synonyms | ODAM; APIN; Odontogenic ameloblast-associated protein; Apin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 16-279 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A1E959 |
|---|
Uniprot Id
A1E959
Target Species
Human
Target Name
ODAM
Target Full Name
Odontogenic ameloblast-associated protein
Target Function
Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.
Target Subcellular Location
Secreted. Cytoplasm. Nucleus.
Target Protein Families
ODAM family
Target Tissue Specificity
Expressed in the junctional epithelium of healthy teeth. In periodontitis, absent in the pocket epithelium of the diseased periodontium but is detected in the gingival crevicular fluid.
Target Research Area
Signal Transduction
Target Synonyms
ODAM; APIN; Odontogenic ameloblast-associated protein; Apin
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