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| Cat.No | ACP10581 | Target Name | OLFML3 |
|---|---|---|---|
| Target Synonyms | HNOEL-iso; hOLF44; OLF44; Olfactomedin like 3; Olfactomedin-like protein 3; OLFL3_HUMAN; OLFML3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 22-406 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NRN5 |
|---|
Uniprot Id
Q9NRN5
Target Species
Human
Target Name
OLFML3
Target Full Name
Olfactomedin-like protein 3
Target Function
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
Target Subcellular Location
Secreted.
Target Protein Families
OLFML3 family
Target Tissue Specificity
Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.
Target Synonyms
HNOEL-iso; hOLF44; OLF44; Olfactomedin like 3; Olfactomedin-like protein 3; OLFL3_HUMAN; OLFML3
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