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| Cat.No | ACP07744 | Target Name | OR4M1 |
|---|---|---|---|
| Target Synonyms | OR4M1; Olfactory receptor 4M1; Olfactory receptor OR14-7 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NGD0 |
|---|
Uniprot Id
Q8NGD0
Target Species
Human
Target Name
OR4M1
Target Full Name
Olfactory receptor 4M1
Target Function
Olfactory receptor that acts as a receptor of Asprosin hormone at the surface of hepatocytes to promote hepatocyte glucose release. Also binds Asprosin in the arcuate nucleus of the hypothalamus, thereby stimulating appetite by promoting orexigenic AgRP neuronal activity. In testis, Asprosin-binding promotes sperm progressive motility and enhances male fertility. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase, resulting in an elevation of intracellular cAMP.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Highly expressed in the testis and olfactory bulb.
Target Synonyms
OR4M1; Olfactory receptor 4M1; Olfactory receptor OR14-7
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