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| Cat.No | ACP15567 | Target Name | SLC51B |
|---|---|---|---|
| Target Synonyms | SLC51B; OSTB; Organic solute transporter subunit beta; OST-beta; Solute carrier family 51 subunit beta | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86UW2 |
|---|
Uniprot Id
Q86UW2
Target Species
Human
Target Name
SLC51B
Target Full Name
Organic solute transporter subunit beta
Target Function
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities.
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Note=Mainly restricted to the lateral and basal membranes of ileal enterocytes.
Target Protein Families
OST-beta family
Target Tissue Specificity
Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat.
Target Synonyms
SLC51B; OSTB; Organic solute transporter subunit beta; OST-beta; Solute carrier family 51 subunit beta
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