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| Cat.No | ACP22582 | Target Name | OSTN |
|---|---|---|---|
| Target Synonyms | OSTN; Osteocrin; Musclin) [Cleaved into: Processed Osteocrin] | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 83-132 |
| Protein Length | Cytoplasmic Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P61366 |
|---|
Uniprot Id
P61366
Target Species
Human
Target Name
OSTN
Target Full Name
Osteocrin
Target Function
Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience. Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex. Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production.
Target Subcellular Location
Secreted.
Target Protein Families
Osteocrin family
Target Tissue Specificity
Enriched in neocortical regions of the developing cerebral cortex. Not expressed in other compartments of the neocortical wall or in brain regions such as the hippocampus, striatum, mediodorsal nucleus of the thalamus and cerebellum. Also expressed in bon
Target Synonyms
OSTN; Osteocrin; Musclin) [Cleaved into: Processed Osteocrin]
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