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Discover the exceptional quality of our Recombinant Human SPP1 protein, a valuable tool for research in cancer biology. Osteopontin, also known as Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, and other names, is a multifunctional glycoprotein involved in cell adhesion, migration, and survival, making it a key player in cancer progression and metastasis. Our Recombinant Human SPP1 protein is the full length of the mature protein of Isoform 5 (17-300aa) expressed in mammalian cells, offering a reliable and functional protein for your experiments. Featuring a C-terminal hFc-Myc tag, our Recombinant Human SPP1 protein enables efficient purification and detection, allowing for seamless integration into your research workflow. With a purity greater than 85% as determined by SDS-PAGE, you can trust the quality and performance of this protein for your cancer research. Available in both liquid and lyophilized powder forms, our Recombinant Human SPP1 protein is designed to meet your specific needs and contribute to your scientific success.
Discover the exceptional quality of our Recombinant Human SPP1 protein, a valuable tool for research in cancer biology. Osteopontin, also known as Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, and other names, is a multifunctional glycoprotein involved in cell adhesion, migration, and survival, making it a key player in cancer progression and metastasis. Our Recombinant Human SPP1 protein is the full length of the mature protein of Isoform 5 (17-300aa) expressed in mammalian cells, offering a reliable and functional protein for your experiments.
Featuring a C-terminal hFc-Myc tag, our Recombinant Human SPP1 protein enables efficient purification and detection, allowing for seamless integration into your research workflow. With a purity greater than 85% as determined by SDS-PAGE, you can trust the quality and performance of this protein for your cancer research. Available in both liquid and lyophilized powder forms, our Recombinant Human SPP1 protein is designed to meet your specific needs and contribute to your scientific success.
| Cat.No | ACP04923 | Target Name | SPP1 |
|---|---|---|---|
| Target Synonyms | bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1; SPP 1; SPP-1; SPP1; SPP1/CALPHA1 fusion; Urinary stone protein; Uropontin | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Expression Range | 17-300aa |
| Mol Weight | 62.2 kDa | Protein Length | Full Length of Mature Protein of Isoform 5 |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P10451 |
|---|
Uniprot Id
P10451
Target Species
Human
Target Name
SPP1
Target Full Name
Osteopontin
Target Function
Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.; Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
Target Subcellular Location
Secreted.
Target Protein Families
Osteopontin family
Target Tissue Specificity
Bone. Found in plasma.
Target Research Area
Cancer
Target Synonyms
BNSP; Bone sialoprotein 1; Bone sialoprotein I; BSP I; BSPI; Early T lymphocyte activation 1; ETA 1; ETA1; MGC110940; Nephropontin; OPN; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; OSTP_HUMAN; PSEC0156; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1; SPP 1; SPP-1; SPP1; SPP1/CALPHA1 fusion; Urinary stone protein; Uropontin
Target Background
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
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