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| Cat.No | ACP23301 | Target Name | CD200 |
|---|---|---|---|
| Target Synonyms | CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD antigen CD200 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 31-232 |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P41217 |
|---|
Uniprot Id
P41217
Target Species
Human
Target Name
CD200
Target Full Name
OX-2 membrane glycoprotein
Target Function
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Research Area
Cardiovascular
Target Synonyms
CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD antigen CD200
Target Background
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
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