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| Cat.No | ACP06958 | Target Name | P2RY1 |
|---|---|---|---|
| Target Synonyms | P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P47900 |
|---|
Uniprot Id
P47900
Target Species
Human
Target Name
P2RY1
Target Full Name
P2Y purinoceptor 1
Target Function
Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor
Target Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
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