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| Cat.No | ACP11603 | Target Name | PAPPA2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BXP8 |
|---|
Uniprot Id
Q9BXP8
Target Species
Human
Target Name
PAPPA2
Target Full Name
Pappalysin-2
Target Function
Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase M43B family
Target Tissue Specificity
Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.
Target Synonyms
PAPPA 2; PAPP E ; PAPP-A2; PAPP-E; PAPP2_HUMAN; PAPPA2; Pappalysin 2 ; Pappalysin-2; PLAC3; Pregnancy associated plasma protein A2; Pregnancy associated plasma protein E1; Pregnancy-associated plasma protein A2; Pregnancy-associated plasma protein E1
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