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Recombinant Human Pappalysin-2 (PAPPA2), Truncated

ACP11603

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11603 Target NamePAPPA2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BXP8
Background Information
  • Uniprot Id

    Q9BXP8

  • Target Species

    Human

  • Target Name

    PAPPA2

  • Target Full Name

    Pappalysin-2

  • Target Function

    Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Peptidase M43B family

  • Target Tissue Specificity

    Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.

  • Target Synonyms

    PAPPA 2; PAPP E ; PAPP-A2; PAPP-E; PAPP2_HUMAN; PAPPA2; Pappalysin 2 ; Pappalysin-2; PLAC3; Pregnancy associated plasma protein A2; Pregnancy associated plasma protein E1; Pregnancy-associated plasma protein A2; Pregnancy-associated plasma protein E1

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