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| Cat.No | ACP19191 | Target Name | PNMA1 |
|---|---|---|---|
| Target Synonyms | 37 kDa neuronal protein; MA1; Neuron- and testis-specific protein 1; Paraneoplastic antigen Ma1; paraneoplastic neuronal antigen MA1; Pnma1; PNMA1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-353 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8ND90 |
|---|
Uniprot Id
Q8ND90
Target Species
Human
Target Name
PNMA1
Target Full Name
Paraneoplastic antigen Ma1
Target Subcellular Location
Nucleus, nucleolus. Note=In tumor cells, it is cytoplasmic.
Target Protein Families
PNMA family
Target Tissue Specificity
Testis- and brain-specific. In some cancer patients, specifically expressed by paraneoplastic tumor cells.
Target Research Area
others
Target Synonyms
37 kDa neuronal protein; MA1; Neuron- and testis-specific protein 1; Paraneoplastic antigen Ma1; paraneoplastic neuronal antigen MA1; Pnma1; PNMA1_HUMAN
Target Background
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors.
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