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Recombinant Human Partitioning defective 6 homolog beta (PARD6B)

ACP12322

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Specifications

Cat.No	ACP12322	Target Name	PARD6B
Target Synonyms	PARD6B; PAR6BPartitioning defective 6 homolog beta; PAR-6 beta; PAR-6B	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-372
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BYG5

Background Information

Uniprot Id

Q9BYG5
Target Species

Human
Target Name

PARD6B
Target Full Name

Partitioning defective 6 homolog beta
Target Function

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Target Subcellular Location

Cytoplasm. Cell membrane. Cell junction, tight junction.
Target Protein Families

PAR6 family
Target Tissue Specificity

Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Target Synonyms

PARD6B; PAR6BPartitioning defective 6 homolog beta; PAR-6 beta; PAR-6B
Target Background

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

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Recombinant Human Partitioning defective 6 homolog beta (PARD6B)

Specifications

Immunogen Information

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