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| Cat.No | ACP14994 | Target Name | PASD1 |
|---|---|---|---|
| Target Synonyms | Cancer/testis antigen 63; CT63; OX-TES-1; PAS domain containing 1; PAS domain-containing protein 1; PASD1; PASD1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-773 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IV76 |
|---|
Uniprot Id
Q8IV76
Target Species
Human
Target Name
PASD1
Target Full Name
Circadian clock protein PASD1
Target Function
Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed.
Target Subcellular Location
[Isoform 1]: Nucleus.; [Isoform 2]: Nucleus.
Target Tissue Specificity
Testis-specific. Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widesp
Target Synonyms
Cancer/testis antigen 63; CT63; OX-TES-1; PAS domain containing 1; PAS domain-containing protein 1; PASD1; PASD1_HUMAN
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