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Recombinant Human PDZ and LIM domain protein 3 (PDLIM3)

ACP04368

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Specifications

Cat.No	ACP04368	Target Name	PDLIM3
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	1-189aa	Mol Weight	36.2kDa
Protein Length	Full Length of Isoform 3	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q53GG5

Background Information

Uniprot Id

Q53GG5
Target Species

Human
Target Name

PDLIM3
Target Full Name

PDZ and LIM domain protein 3
Target Function

May play a role in the organization of actin filament arrays within muscle cells.
Target Subcellular Location

Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines.
Target Tissue Specificity

Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific.
Target Research Area

Signal Transduction
Target Synonyms

Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3
Target Background

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.

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Recombinant Human PDZ and LIM domain protein 3 (PDLIM3)

Specifications

Immunogen Information

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