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| Cat.No | ACP16106 | Target Name | Paox |
|---|---|---|---|
| Target Synonyms | PAOX; PAO; UNQ1923/PRO4398Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; EC 1.5.3.13; Polyamine oxidase | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-649 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6QHF9 |
|---|
Uniprot Id
Q6QHF9
Target Species
Human
Target Name
PAOX
Target Full Name
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Target Function
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Target Subcellular Location
Peroxisome. Cytoplasm.
Target Protein Families
Flavin monoamine oxidase family
Target Tissue Specificity
Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.
Target Synonyms
PAOX; PAO; UNQ1923/PRO4398Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; EC 1.5.3.13; Polyamine oxidase
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