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| Cat.No | ACP13656 | Target Name | PSD4 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NDX1 |
|---|
Uniprot Id
Q8NDX1
Target Species
Human
Target Name
PSD4
Target Full Name
PH and SEC7 domain-containing protein 4
Target Function
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Target Subcellular Location
Cell membrane. Cell projection, ruffle membrane.
Target Tissue Specificity
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
Target Synonyms
EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Ppleckstrin and Sec7 domain containing 4 ; PSD4; PSD4_HUMAN; SEC7 homolog | telomeric of interleukin-1 cluster protein; Telomeric of interleukin-1 cluster protein; TIC
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