Home Products Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2), Truncated

Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2), Truncated

ACP16504

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Specifications

Cat.No	ACP16504	Target Name	PREX2
Target Synonyms	4, 5-trisphosphate-dependent Rac exchange factor 2; PREX2; PREX2_HUMAN; PtdIns(3; PtdIns(3, 5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol-3, 5-trisphosphate-dependent Rac exchanger 2; phosphatidylinositol 3, 5)-dependent Rac exchanger 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q70Z35

Background Information

Uniprot Id

Q70Z35
Target Species

Human
Target Name

PREX2
Target Full Name

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
Target Function

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Target Tissue Specificity

Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.
Target Synonyms

4; 5)-dependent Rac exchanger 2; 5-trisphosphate-dependent Rac exchanger 2 protein; 6230420N16Rik; DEP domain-containing protein 2; DEP.2; DEPDC2; FLJ12987; P-Rex2; Phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; PREX2; PREX2_HUMAN; PtdIns(3; PtdIns(3,4,5)-dependent Rac exchanger 2

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Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2), Truncated Now

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