-
Chinese (Simplified)
-
English
-
German
-
Korean
-
Spanish
Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP19521 | Target Name | PACS2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VP3 |
|---|
Uniprot Id
Q86VP3
Target Species
Human
Target Name
PACS2
Target Full Name
Phosphofurin acidic cluster sorting protein 2
Target Function
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Target Subcellular Location
Endoplasmic reticulum. Mitochondrion.
Target Protein Families
PACS family
Target Tissue Specificity
Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis.
Target Synonyms
6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; KIAA0602; mKIAA0602; PACS 2; PACS-2; PACS1 like protein; PACS1-like protein; PACS1L; PACS2; PACS2_HUMAN; Phosphofurin acidic cluster sorting protein 1 like; Phosphofurin acidic cluster sorting protein 2
Notification