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Recombinant Human Phosphoglycerate kinase 2 (PGK2)

ACP22371

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22371 Target NamePGK2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-417Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP07205
Background Information
  • Uniprot Id

    P07205

  • Target Species

    Human

  • Target Name

    PGK2

  • Target Full Name

    Phosphoglycerate kinase 2

  • Target Function

    Essential for sperm motility and male fertility. Not required for the completion of spermatogenesis.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Phosphoglycerate kinase family

  • Target Tissue Specificity

    Mainly found in round spermatids. Localized on the principle piece in the sperm (at protein level). Testis-specific. Expression significantly decreased in the testis of elderly men.

  • Target Synonyms

    dJ417L20.2; PGK 2; pgk2; PGK2_HUMAN; PGKB; PGKPS; Phosphoglycerate kinase 2; Phosphoglycerate kinase; Phosphoglycerate kinase autosomal pseudogene; Phosphoglycerate kinase testis specific; testis specific

  • Target Background

    This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1, 3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.

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