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| Cat.No | ACP19115 | Target Name | PLSCR4 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NRQ2 |
|---|
Uniprot Id
Q9NRQ2
Target Species
Human
Target Name
PLSCR4
Target Full Name
Phospholipid scramblase 4
Target Function
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Protein Families
Phospholipid scramblase family
Target Tissue Specificity
Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes.
Target Synonyms
AV245873; Ca(2+)-dependent phospholipid scramblase 4; Cell growth inhibiting protein 43; Cell growth-inhibiting gene 43 protein; GIG43; Phospholipid scramblase 4; PL scramblase 4; Pls4; PLS4_HUMAN; Plscr4; TRA1
Target Background
Enables CD4 receptor binding activity and enzyme binding activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to act upstream of or within cellular response to lipopolysaccharide. Located in plasma membrane.
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