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| Cat.No | ACP11861 | Target Name | PITHD1 |
|---|---|---|---|
| Target Synonyms | PITHD1; C1orf128; AD039; HT014; PP603; PITH domain-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-211 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9GZP4 |
|---|
Uniprot Id
Q9GZP4
Target Species
Human
Target Name
PITHD1
Target Full Name
PITH domain-containing protein 1
Target Function
Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene.
Target Subcellular Location
Cytoplasm.
Target Protein Families
PITHD1 family
Target Tissue Specificity
Down-regulated in primary acute myeloid leukemia (AML) patients.
Target Research Area
Others
Target Synonyms
PITHD1; C1orf128; AD039; HT014; PP603; PITH domain-containing protein 1
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