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| Cat.No | ACP24065 | Target Name | ADCYAP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 82-129 | Protein Length | Cytoplasmic Domain |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P18509 |
|---|
Uniprot Id
P18509
Target Species
Human
Target Name
ADCYAP1
Target Full Name
Pituitary adenylate cyclase-activating polypeptide
Target Function
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.
Target Subcellular Location
Secreted.
Target Protein Families
Glucagon family
Target Synonyms
ADCYAP1Pituitary adenylate cyclase-activating polypeptide; PACAP) [Cleaved into: PACAP-related peptide; PRP-48); Pituitary adenylate cyclase-activating polypeptide 27; PACAP-27; PACAP27); Pituitary adenylate cyclase-activating polypeptide 38; PACAP-38; PACAP38)]
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