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Recombinant Human Plasma membrane calcium-transporting ATPase 3 (ATP2B3), Truncated

ACP06219

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06219 Target NameATP2B3
Target SynonymsATP2B3Plasma membrane calcium-transporting ATPase 3; PMCA3; EC 7.2.2.10; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ16720
Background Information
  • Uniprot Id

    Q16720

  • Target Species

    Human

  • Target Name

    ATP2B3

  • Target Full Name

    Plasma membrane calcium-transporting ATPase 3

  • Target Function

    ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment. May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established.

  • Target Involvement

    Spinocerebellar ataxia, X-linked 1 (SCAX1)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, presynaptic cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIB subfamily

  • Target Tissue Specificity

    Highly expressed in the cerebellum. Expressed in adrenal glands.

  • Target Synonyms

    ATP2B3Plasma membrane calcium-transporting ATPase 3; PMCA3; EC 7.2.2.10; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3

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