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| Cat.No | ACP06219 | Target Name | ATP2B3 |
|---|---|---|---|
| Target Synonyms | ATP2B3Plasma membrane calcium-transporting ATPase 3; PMCA3; EC 7.2.2.10; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16720 |
|---|
Uniprot Id
Q16720
Target Species
Human
Target Name
ATP2B3
Target Full Name
Plasma membrane calcium-transporting ATPase 3
Target Function
ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment. May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established.
Target Involvement
Spinocerebellar ataxia, X-linked 1 (SCAX1)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, presynaptic cell membrane; Multi-pass membrane protein.
Target Protein Families
Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIB subfamily
Target Tissue Specificity
Highly expressed in the cerebellum. Expressed in adrenal glands.
Target Synonyms
ATP2B3Plasma membrane calcium-transporting ATPase 3; PMCA3; EC 7.2.2.10; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3
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