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| Cat.No | ACP10620 | Target Name | PLEKHA3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-300 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HB20 |
|---|
Uniprot Id
Q9HB20
Target Species
Human
Target Name
PLEKHA3
Target Full Name
Pleckstrin homology domain-containing family A member 3
Target Function
Plays a role in regulation of vesicular cargo transport from the trans-Golgi network (TGN) to the plasma membrane. Regulates Golgi phosphatidylinositol 4-phosphate (PtdIns(4)P) levels and activates the PtdIns(4)P phosphatase activity of SACM1L when it binds PtdIns(4)P in 'trans' configuration. Binds preferentially to PtdIns(4)P. Negatively regulates APOB secretion from hepatocytes.
Target Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Target Tissue Specificity
Widely expressed.
Target Synonyms
PLEKHA3; FAPP1; Pleckstrin homology domain-containing family A member 3; PH domain-containing family A member 3; Phosphatidylinositol-four-phosphate adapter protein 1; FAPP-1; Phosphoinositol 4-phosphate adapter protein 1
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