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Recombinant Human Pleckstrin homology domain-containing family A member 7 (PLEKHA7), Truncated

ACP16257

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16257 Target NamePLEKHA7
Target SynonymsDKFZp686M22243; PH domain-containing family A member 7; PKHA7_HUMAN; Pleckstrin homology domain containing family A member 2; Pleckstrin homology domain-containing family A member 7; Plekha7FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6IQ23
Background Information
  • Uniprot Id

    Q6IQ23

  • Target Species

    Human

  • Target Name

    PLEKHA7

  • Target Full Name

    Pleckstrin homology domain-containing family A member 7

  • Target Function

    Required for zonula adherens biogenesis and maintenance. Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site. Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33.

  • Target Subcellular Location

    Cell junction, adherens junction. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

  • Target Synonyms

    DKFZp686M22243; PH domain-containing family A member 7; PKHA7_HUMAN; Pleckstrin homology domain containing family A member 2; Pleckstrin homology domain-containing family A member 7; Plekha7

  • Target Background

    Enables delta-catenin binding activity. Involved in epithelial cell-cell adhesion; pore complex assembly; and zonula adherens maintenance. Located in several cellular components, including centrosome; nucleoplasm; and zonula adherens. Part of pore complex.

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