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| Cat.No | ACP21319 | Target Name | PLXNB1 |
|---|---|---|---|
| Target Synonyms | PLXNB1; KIAA0407; PLXN5; SEP; Plexin-B1; Semaphorin receptor SEP | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43157 |
|---|
Uniprot Id
O43157
Target Species
Human
Target Name
PLXNB1
Target Full Name
Plexin-B1
Target Function
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Target Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.
Target Protein Families
Plexin family
Target Tissue Specificity
Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.
Target Research Area
Neuroscience
Target Synonyms
PLXNB1; KIAA0407; PLXN5; SEP; Plexin-B1; Semaphorin receptor SEP
Target Background
Enables semaphorin receptor activity. Involved in several processes, including negative regulation of cell adhesion; regulation of cell shape; and semaphorin-plexin signaling pathway. Is integral component of plasma membrane. Part of semaphorin receptor complex.
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