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Recombinant Human Polyadenylate-binding protein-interacting protein 2 (PAIP2)

ACP12484

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Specifications

Cat.No	ACP12484	Target Name	PAIP2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-127	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BPZ3

Background Information

Uniprot Id

Q9BPZ3
Target Species

Human
Target Name

PAIP2
Target Full Name

Polyadenylate-binding protein-interacting protein 2
Target Function

Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Target Subcellular Location

Cytoplasm.
Target Protein Families

PAIP2 family
Target Tissue Specificity

Expressed at highest level in testis, but also abundant in brain, cervix, lung, ovary, placenta, adipose tissue, thymus and thyroid.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

PABP-interacting protein 2; PAIP-2; PAIP2; PAIP2_HUMAN; poly(A) binding protein interacting protein 2; Poly(A)-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2

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Recombinant Human Polyadenylate-binding protein-interacting protein 2 (PAIP2)

Specifications

Immunogen Information

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