Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3), Truncated

Cat.No	ACP18476	Target Name	GALNT3
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP18476

Target Name

GALNT3

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q14435

Background Information

Uniprot Id

Q14435
Target Species

Human
Target Name

GALNT3
Target Full Name

Polypeptide N-acetylgalactosaminyltransferase 3
Target Function

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis.
Target Involvement

Tumoral calcinosis, hyperphosphatemic, familial (HFTC)
Target Subcellular Location

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Resides preferentially in the trans and medial parts of the Golgi stack.
Target Protein Families

Glycosyltransferase 2 family, GalNAc-T subfamily
Target Tissue Specificity

Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney.
Target Synonyms

DKFZp686C10199; EC 2.4.1.41; GalNAc T3; GalNAc transferase 3; GalNAc-T3; GalNAcT3; GALNT3; GALT3_HUMAN; HFTC; HHS; MGC61909; OTTHUMP00000204915; OTTHUMP00000204919; Polypeptide GalNAc transferase 3; Polypeptide GalNAc transferase T3; Polypeptide N acetylgalactosaminyltransferase 3; Polypeptide N-acetylgalactosaminyltransferase 3; pp-GaNTase 3; ppGaNTase 3; Protein UDP acetylgalactosaminyltransferase 3; Protein-UDP acetylgalactosaminyltransferase 3; RP23-306G16.2; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 3 ; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 3 (GalNAc T3); UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
Target Background

This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities.

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3), Truncated Now

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