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| Cat.No | ACP05426 | Target Name | KCNU1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A8MYU2 |
|---|
Uniprot Id
A8MYU2
Target Species
Human
Target Name
KCNU1
Target Full Name
Potassium channel subfamily U member 1
Target Function
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa5.1/KCNU1 sub-subfamily
Target Tissue Specificity
Testis-specific.
Target Synonyms
subfamily M subunit alpha-3; Calcium activated potassium channel subfamily M subunit alpha 3; Calcium activated potassium channel subunit alpha 3; Calcium-activated potassium channel; Calcium-activated potassium channel subunit alpha-3; KCa5; KCa5.1; Kcnma3; KCNMC1; KCNU 1; KCNU1; KCNU1_HUMAN; Potassium channel subfamily U member 1; Slo3; Slowpoke homolog 3
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