Recombinant Human POU domain, class 3, transcription factor 4 (POU3F4)

Uniprot Id

P49335

Target Species

Human

Target Name

POU3F4

Target Full Name

POU domain, class 3, transcription factor 4

Target Function

Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.

Target Involvement

Deafness, X-linked, 2 (DFNX2)

Target Subcellular Location

Nucleus.

Target Protein Families

POU transcription factor family, Class-3 subfamily

Target Tissue Specificity

Brain specific.

Target Synonyms

Brain specific homeobox POU domain protein 4; Brain-4; Brain-specific homeobox/POU domain protein 4; BRAIN4; Brn-4; BRN4; class 3; DFN3; DFNX2; Oct-9; Octamer-binding protein 9; Octamer-binding transcription factor 9; OTF-9; OTF9; PO3F4_HUMAN; POU class 3 homeobox 4; POU domain; POU domain class 3 transcription factor 4; Pou3f4; transcription factor 4

Target Background

This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.