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Recombinant Human Pre-mRNA-splicing factor SPF27 (BCAS2)

ACP20867

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Specifications

Cat.No	ACP20867	Target Name	BCAS2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-225	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O75934

Background Information

Uniprot Id

O75934
Target Species

Human
Target Name

BCAS2
Target Full Name

Pre-mRNA-splicing factor SPF27
Target Function

Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Target Subcellular Location

Nucleus. Nucleus, nucleolus.
Target Protein Families

SPF27 family
Target Tissue Specificity

Ubiquitously expressed.
Target Research Area

Tags & Cell Markers
Target Synonyms

bcas2; Breast carcinoma amplified sequence 2; Breast carcinoma-amplified sequence 2; DAM 1; DAM-1; DAM1; DNA amplified in mammary carcinoma 1 protein; MGC7712; Pre mRNA splicing factor SPF27; Pre-mRNA-splicing factor spf27; Snt309; SPF27; SPF27_HUMAN; Spliceosome associated protein amplified in breast cancer; Spliceosome associated protein SPF 27; Spliceosome-associated protein SPF 27
Target Background

Involved in mRNA splicing, via spliceosome. Located in centrosome and nuclear speck. Part of U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex. Implicated in breast cancer.

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Recombinant Human Pre-mRNA-splicing factor SPF27 (BCAS2)

Specifications

Immunogen Information

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