Recombinant Human Pro-neuregulin-2, membrane-bound isoform (NRG2)

ACP09161

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Specifications

Cat.No	ACP09161	Target Name	NRG2
Target Synonyms	Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2_HUMAN; NTAK; Pro NRG2; Pro-NRG2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	112-405
Protein Length	Extracellular Domain	Purity	Greater than 85% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O14511

Background Information

Uniprot Id

O14511
Target Species

Human
Target Name

NRG2
Target Full Name

Pro-neuregulin-2, membrane-bound isoform
Target Function

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Target Subcellular Location

[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-2]: Secreted.
Target Protein Families

Neuregulin family
Target Tissue Specificity

Restricted to the cerebellum in the adult.
Target Research Area

Neuroscience
Target Synonyms

Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2_HUMAN; NTAK; Pro NRG2; Pro-NRG2

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Recombinant Human Pro-neuregulin-2, membrane-bound isoform (NRG2)

Specifications

Immunogen Information

Inquire Recombinant Human Pro-neuregulin-2, membrane-bound isoform (NRG2) Now

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