Recombinant Human Probable E3 ubiquitin-protein ligase MID2 (MID2)

Uniprot Id

Q9UJV3

Target Species

Human

Target Name

MID2

Target Full Name

Probable E3 ubiquitin-protein ligase MID2

Target Function

May play a role in microtubule stabilization.

Target Involvement

Mental retardation, X-linked 101 (MRX101)

Target Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.

Target Protein Families

TRIM/RBCC family

Target Tissue Specificity

Low level in fetal kidney and lung, and in adult prostate, ovary and small intestine.

Target Synonyms

FLJ37715; FLJ41813; FXY2; MID2; Midin 2; Midin-2; Midline 2; Midline defect 2; Midline-2; probable E3 ubiquitin protein ligase MID2; Probable E3 ubiquitin-protein ligase MID2; RING finger protein 60; Ring finger protein protein 60; RNF60; TRIM1; TRIM1_HUMAN; tripartite motif containing protein 1; Tripartite motif protein 1; Tripartite motif-containing protein 1

Target Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms.