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| Cat.No | ACP05993 | Target Name | ADGRA3 |
|---|---|---|---|
| Target Synonyms | ADGRA3; GPR125; UNQ556/PRO1113Adhesion G protein-coupled receptor A3; G-protein coupled receptor 125 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IWK6 |
|---|
Uniprot Id
Q8IWK6
Target Species
Human
Target Name
ADGRA3
Target Full Name
Adhesion G protein-coupled receptor A3
Target Function
Orphan receptor that may have a role in planar cell polarity pathway.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Synonyms
ADGRA3; GPR125; UNQ556/PRO1113Adhesion G protein-coupled receptor A3; G-protein coupled receptor 125
Target Background
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia.
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