Home Products Recombinant Human Probable G-protein coupled receptor 75 (GPR75), Truncated,Mammalian cell

Recombinant Human Probable G-protein coupled receptor 75 (GPR75), Truncated,Mammalian cell

ACP08686

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Specifications

Cat.No	ACP08686	Target Name	GPR75
Target Synonyms	G protein coupled receptor 75; GPR chr2; Gpr75; GPR75_HUMAN; GPRchr2; OTTHUMP00000159608; Probable G protein coupled receptor 75; Probable G-protein coupled receptor 75; WI 31133; WI31133	Form	Liquid or Lyophilized powder
Expression System	Mammalian cell	Mol Weight	20.9kDa
Protein Length	Partial	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95800

Background Information

Uniprot Id

O95800
Target Species

Human
Target Name

GPR75
Target Full Name

Probable G-protein coupled receptor 75
Target Function

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family
Target Tissue Specificity

Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cel
Target Research Area

Signal Transduction
Target Synonyms

G protein coupled receptor 75; GPR chr2; Gpr75; GPR75_HUMAN; GPRchr2; OTTHUMP00000159608; Probable G protein coupled receptor 75; Probable G-protein coupled receptor 75; WI 31133; WI31133

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Recombinant Human Probable G-protein coupled receptor 75 (GPR75), Truncated,Mammalian cell

Specifications

Immunogen Information

Inquire Recombinant Human Probable G-protein coupled receptor 75 (GPR75), Truncated,Mammalian cell Now

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