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| Cat.No | ACP07703 | Target Name | ZDHHC16 |
|---|---|---|---|
| Target Synonyms | ZDHHC16; APH2; UNQ2570/PRO6258; Palmitoyltransferase ZDHHC16; Abl-philin 2; Zinc finger DHHC domain-containing protein 16; DHHC-16 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q969W1 |
|---|
Uniprot Id
Q969W1
Target Species
Human
Target Name
ZDHHC16
Target Full Name
Palmitoyltransferase ZDHHC16
Target Function
Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6. Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization. Also required for eye development. Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function. May play a role in DNA damage response. May be involved in apoptosis regulation. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
DHHC palmitoyltransferase family
Target Tissue Specificity
Widely expressed.
Target Synonyms
ZDHHC16; APH2; UNQ2570/PRO6258; Palmitoyltransferase ZDHHC16; Abl-philin 2; Zinc finger DHHC domain-containing protein 16; DHHC-16
Target Background
Enables palmitoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus.
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